Improving Solubility For Pharmaceutical Applications With Polysorbate Tween80
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Improving Solubility For Pharmaceutical Applications With Polysorbate Tween80

Improving Solubility For Pharmaceutical Applications With Polysorbate Tween80

Polysorbate Tween80 is a valuable excipient that plays a crucial role in improving drug solubility and enhancing pharmaceutical outcomes. Its various benefits, from increased bioavailability to improved patient compliance, make it an indispensable ingredient in modern drug formulation.

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Product Introduction

 

Product Introduction

Polysorbate Tween80 enables the formulation of a broader range of drug delivery systems, including solutions, suspensions, emulsions, and micro/nano-particles. This versatility allows pharmaceutical developers to choose the most appropriate dosage form for their specific drug and target population.

 

 

Products Parameters

 

CHEMICAL/PHYSICAL SPECIFICATIONS
Acid value ≤2.0 mg KOH/g
Saponification value 45-55 mg KOH/g
Hydroxyl value 65~80 mg KOH/g
Moisture ≤3.0 w/%
Residue on ignition ≤0.25 w/%
Oxyethylen 65.0~69.5 w/%
HEAVY METAL SPECIFICATIONS
Arsenic
Lead
≤ 3
≤ 2
mg/kg
mg/kg

 

 

Features

1.Enhanced bioavailability: Polysorbate Tween80 improves the solubility of hydrophobic drugs, which in turn increases their bioavailability. Higher bioavailability results in more effective treatment and ultimately better patient outcomes.

2.Increased stability: Polysorbate Tween80 can also improve the stability of drugs, which may result in a longer shelf life. This is especially important in situations where drugs need to be stored for extended periods of time or during transportation.

3. Improved manufacturing efficiency: With the help of Polysorbate Tween80, pharmaceutical companies can manufacture drugs that are more soluble and stable, leading to higher production and efficiency. This can ultimately translate into lower costs and more affordable medication for patients.
 

 

 

Application

1. Enhances Bioavailability: The poor aqueous solubility of many drug molecules can pose a challenge to their absorption and bioavailability. By improving solubility, Polysorbate Tween80 can enhance the rate and extent of drug absorption, leading to improved clinical outcomes.

2. Increases Stability: Poorly soluble drugs are often subjected to degradation, which can result in reduced efficacy or adverse effects. Polysorbate Tween80 acts as a stabilizer by preventing the precipitation or aggregation of drug molecules, thereby ensuring their integrity and activity.

3. Reduces Dose: When a drug is poorly soluble, it often requires a higher dose to achieve therapeutic effects. However, by improving solubility, Polysorbate Tween80 can reduce the required dose, thereby minimizing the risk of toxicity and side effects.

4. Improves Patient Compliance: High-dose medications and frequent dosing regimens can impact patient adherence and compliance. By reducing the dose and frequency of administration, Polysorbate Tween80 can improve the convenience and acceptability of drug therapy, leading to better patient outcomes.

 

 

Package

Plastic drum
Net Weight:200kg ;
Gross Weight:209kg
Pack size:
Inner diameter:58cm ; Height:90cm
20GP:80 drums,16mts with or without
pallets
40GP:116 drums,23.2mts with or without
pallets
IBC drum
Net Weight:1000kg/IBC drum;
Gross Weight:1058kg
Pack size:120*100*115cm
20GP:20 drums,20mts with or without
pallets
40GP:25 drums,25mts with or without pallets

 

 

Advantages & Characteristics
  • Kosher/Halal/ISO9001/ISO22000/RSPOCerificated
  • No MOQ,More Opportunities
  • Customized Products
  • Mixed Shipment
 

ISO9001

 

FAQS

Q: Can i get your COA,TDS and MSDS?

A: Sure! Contact us marketing@cnchemsino.com or the sales manager.

Q: Do you have the RSPO certificate?

A: Yes. We have RSPO, Kosher, Halal, ISO9001 and ISO22000 certificates.

Q: Can you do the customized package?

A: Yes. Our common package is 25kg/bag/carton/drum with the powder, and 200kg/drum or 1000kgs/IBC Drum with the liquid. Special package according to the requirements of our customers.

Q: How long of the delivery time?

A: Usually, the shipment can be delivery within 15-20days after the order confirmed.

Q: Can i get the free sample?

A: Yes, sample can be free below 500g.

Q: How about the MOQ?

A: No MOQ, More Opportunities

Q: How about the payment items?

A: L/C, D/P, D/A,CAD,T/T; Long time payment is also available.

Q: Which country have you exported to?

A: Our main market is South America, Middle East, Africa and Europe. More than 50 countries.

Q:  Can i visit your factory?

A: Sure! Welcome in any time.

Q: Can you support us in the applications?

A: It is our pleasure!

Q: Can you accept the inspection from a third party?

A: Yes. We have enough experience to cooperate with the inspection project.

 

 

 

 

 

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