Improving The Solubility Of Medicines With Polysorbates Liquid
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Improving The Solubility Of Medicines With Polysorbates Liquid

Improving The Solubility Of Medicines With Polysorbates Liquid

Polysorbates are surface-active agents that are widely used in the pharmaceutical industry to enhance the solubility of poorly soluble drugs.

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Product Introduction

 

Product Introduction

Polysorbates are substances that help drugs dissolve better even if they don't easily mix with liquids. They're often used in medicine, and are made from sorbitol, fatty acids, and ethylene oxide. Polysorbates are grouped by how much of the ethylene oxide they contain.

 

 

Products Parameters

 

CHEMICAL/PHYSICAL SPECIFICATIONS
Acid value ≤2.0 mg KOH/g
Saponification value 40~50 mg KOH/g
Hydroxyl value 96~108 mg KOH/g
Moisture ≤3.0 w/%
Residue on ignition ≤0.25 mg/kg
Oxyethylene 70.0~74.0 w/%
HEAVY METAL SPECIFICATIONS
Arsenic
Cadmium
Heavy Metal as Pb
≤ 3
≤ 1
≤ 2
mg/kg
mg/kg
mg/kg

 

 

Features

Improving the solubility of medicines is crucial for enhancing their effectiveness and improving patient outcomes. Polysorbates liquid is a safe and effective solubilizing agent that can help to enhance the solubility of poorly soluble drugs. Its non-toxic, non-irritating, and non-sensitizing properties make it an ideal choice for use in a wide range of drug formulations. With the use of polysorbates, drug manufacturers can develop more effective treatments for patients suffering from a wide range of conditions.

 

 

Application

Polysorbates work by forming micelles around the poorly soluble drugs, which helps to disperse them in water. The hydrophobic tails of the polysorbate molecules attach to the drug, while the hydrophilic heads remain in the water. As a result, the drug becomes more soluble and easier to administer.

Polysorbates have several advantages over other solubilizing agents. They are non-toxic, non-irritating, and non-sensitizing, which makes them safe for human consumption. They are also compatible with a wide range of drugs and have a low risk of interacting with other excipients.

Another advantage of polysorbates is that they can improve the bioavailability of drugs. Bioavailability refers to the percentage of a drug that enters the bloodstream and reaches its target site. Many poorly soluble drugs have low bioavailability, which means that only a small percentage of the drug is absorbed by the body. By enhancing the solubility of these drugs, polysorbates can increase their bioavailability and improve their effectiveness.

Polysorbates are commonly used in a variety of medicines, including injectable formulations, oral suspensions, and topical creams. They are particularly useful for lipophilic drugs, which are drugs that dissolve in fats and oils. These drugs are often used to treat conditions such as cancer, cardiovascular disease, and central nervous system disorders.

 

 

Package

25KG/Drum

 

 

Advantages & Characteristics
  • Kosher/Halal/ISO9001/ISO22000/RSPOCerificated
  • No MOQ,More Opportunities
  • Customized Products
  • Mixed Shipment
 

ISO9001

 

FAQS

Q: Can i get your COA,TDS and MSDS?

A: Sure! Contact us marketing@cnchemsino.com or the sales manager.

Q: Do you have the RSPO certificate?

A: Yes. We have RSPO, Kosher, Halal, ISO9001 and ISO22000 certificates.

Q: Can you do the customized package?

A: Yes. Our common package is 25kg/bag/carton/drum with the powder, and 200kg/drum or 1000kgs/IBC Drum with the liquid. Special package according to the requirements of our customers.

Q: How long of the delivery time?

A: Usually, the shipment can be delivery within 15-20days after the order confirmed.

Q: Can i get the free sample?

A: Yes, sample can be free below 500g.

Q: How about the MOQ?

A: No MOQ, More Opportunities

Q: How about the payment items?

A: L/C, D/P, D/A,CAD,T/T; Long time payment is also available.

Q: Which country have you exported to?

A: Our main market is South America, Middle East, Africa and Europe. More than 50 countries.

Q:  Can i visit your factory?

A: Sure! Welcome in any time.

Q: Can you support us in the applications?

A: It is our pleasure!

Q: Can you accept the inspection from a third party?

A: Yes. We have enough experience to cooperate with the inspection project.

 

 

 

 

 

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