Polysorbates Liquid: The Trusted Emulsifier For Drug Delivery Systems CAS NO.9005-65-6
Polysorbates are synthesized by chemical esterification of sorbitan and polyols that are derived from fats and oils. They are commonly known as surfactants, as they can lower the surface tension between two immiscible phases.
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Product Introduction
Product Introduction
Polysorbates are created by mixing sorbitan and polyols from fats and oils. They are used as surfactants to reduce the surface tension between different substances. They are particularly helpful in making emulsions by blending oil droplets into water to create a consistent mixture. Polysorbates are an important component in many products because of this useful ability.
Products Parameters
| CHEMICAL/PHYSICAL SPECIFICATIONS | ||
| Acid value | ≤2.0 | mg KOH/g |
| Saponification value | 45-55 | mg KOH/g |
| Hydroxyl value | 65~80 | mg KOH/g |
| Moisture | ≤3.0 | w/% |
| Residue on ignition | ≤0.25 | w/% |
| Oxyethylen | 65.0~69.5 | w/% |
| HEAVY METAL SPECIFICATIONS | ||
| Arsenic Lead |
≤ 3 ≤ 2 |
mg/kg mg/kg |
Features
Polysorbates liquid is a versatile emulsifier and stabilizer with excellent properties that make it a trusted ingredient in drug delivery systems. Its ability to solubilize poorly water-soluble drugs, stabilize liposomal drug formulations, and improve drug bioavailability in oral drug delivery systems has made it an indispensable ingredient in pharmaceutical formulations.
Application
In drug delivery systems, polysorbates are used as emulsifiers, solubilizers, and stabilizers to enhance the properties of the formulations. Polysorbates liquid is the most commonly used form of polysorbates in pharmaceuticals. It is a clear, colorless liquid that is soluble in water and many organic solvents. Polysorbates liquid is available in different grades depending on the specific requirements of the intended application.
Polysorbates liquid is commonly used in the formulation of liposomal drug delivery systems. A liposomal drug delivery system is a type of drug delivery system that involves encapsulating the drug molecules within a lipid bilayer using liposomes. The use of polysorbates liquid as a stabilizer in liposome formulations reduces the likelihood of drug leakage and degradation, thereby increasing the shelf-life of the drug product.
Polysorbates liquid is also widely used in the formulation of intravenous (IV) drug delivery systems. IV drug delivery is a method of drug administration that involves injecting drugs directly into the bloodstream. IV drug delivery is preferred for drugs that require rapid onset of action, or for drugs that cannot be administered orally. Polysorbates liquid is used in IV drug formulations to solubilize poorly water-soluble drugs, thereby enabling their efficient delivery.
Polysorbates liquid is also used as an emulsifier in oral drug delivery systems. Oral drug delivery is a common method of drug administration, as it is convenient and easy to administer. However, many drugs are poorly water-soluble, making their delivery through oral routes challenging. Polysorbates liquid improves the bioavailability of poorly water-soluble drugs in oral drug delivery systems, thereby increasing their therapeutic efficacy.
Package
25kg/drum
Advantages & Characteristics
- Kosher/Halal/ISO9001/ISO22000/RSPOCerificated
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- Mixed Shipment

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